ATWATER, Calif. (AP) — The six most seriously injured people in a deadly California bus crash are out of critical condition.

Dr. Kathleen Eve, trauma surgeon at Doctors Medical Center of Modesto, said Tuesday that three patients are now in serious condition and three are in fair condition.

Eve says some had head and neck injuries along with broken bones, and some amputations had to be performed but she did not elaborate. Some remain on ventilators and are unconscious, but their vital signs are stable.

She said the patients she treated, whose ages range from 30s to 50s, will need to be in the hospital between two days and a week.

Twelve other patients with less serious injuries were treated at other hospitals.

Five people were killed in the charter bus crash on a highway in the state's agricultural Central Valley.