Edinson Volquez pitched into the eighth inning and Jedd Gyorko and Alexi Amarista each homered, and the San Diego Padres beat the Seattle Mariners 6-1 on Tuesday.

The teams split the brief two-game set in Seattle, but will be right back at it on Wednesday in San Diego for two more games as the "natural rivals" conclude their season series.

Gyorko hit a two-run shot in the fourth inning off Seattle starter Brandon Maurer, his sixth homer of the season. Amarista followed with a solo shot an inning later and the Padres knocked out Maurer (2-7) with three runs in the sixth as they won for just the second time in the past seven games.

Seattle's bats got very little done against Volquez (4-5) and its lineup lost its most potent punch after right fielder Michael Morse had to leave the game in the fifth inning.

Right fielder Michael Morse left the game against after sustaining a right quadriceps strain on a play in which he was thrown out trying to score from first base on a double.

Morse was lifted Tuesday night in the top of the fifth inning. Morse became the second out of the bottom of the fourth after he was thrown out at home plate trying to score on a double from Michael Saunders. Morse was laboring as he reached third and was grimacing as he attempted to score after getting waved home by third base coach Daren Brown. Morse was easily thrown out.

Morse is day to day. He was replaced in the lineup by Jason Bay.

Morse missed three games in April with a small fracture in his right little finger.